///2017 Abstract Details
2017 Abstract Details2019-08-02T15:54:53-05:00

Incidence, co morbidities and outcomes in parturients with pheochromocytoma: Analysis from the National Inpatient Sample

Abstract Number: SAT-18
Abstract Type: Original Research

Rabab Nasim MD1 ; Junaid Nizamuddin MD2; Sarosh Rana MD3; Sajid Shahul MD4

Incidence, co morbidities and outcomes in parturients with pheochromocytoma: Analysis from the National Inpatient Sample

BACKGROUND: Pheochromocytoma is a rare cause of hypertension in pregnancy (1). Prior studies have suggested that pheochromocytoma worsens maternal outcomes; however, there is a paucity of data about the incidence of pheochromocytoma in pregnancy and associated comorbidities and complications. Using a large national database, we examined the incidence, comorbidities and outcomes of pheochromocytoma in pregnancy,

METHODS: We performed a retrospective cohort analysis using data from the National Inpatient Sample (NIS) from 2002 to 2013. The NIS database is the largest inpatient healthcare database in the United States and provides discharge data on approximately seven million hospital stays annually. It is maintained by the Healthcare Utilization Project (HCUP) of the Agency for Healthcare Quality and Research. The NIS approximates a 20% stratified sample of all discharges from all HCUP hospitals (N= 4,924 in 2013). National estimates are obtained by weighting NIS data to provide data estimates for 95% of all inpatient hospitalization in the United States.

RESULTS: Among 53523298 deliveries, 671 (1.25/100,000 hospitalization) had an associated diagnosis of pheochromocytoma. Parturients with pheochromocytoma experienced a higher mortality (1.4%) than healthy parturients (0.02%), although this was not statistically significant (p=0.16). Pheochromocytoma was associated with an increased incidence of Congestive heart failure (CHF), Peripartum cardiomyopathy (PPCM), hypertension, preeclampsia, renal failure and metabolic abnormalities (See Table).

CONCLUSION: Pheochromocytoma is associated with worse maternal outcomes and increased morbidity and mortality in pregnancy. Furtherwork needs to be performed to better improve outcomes in these patients

REFERENCES:

1Harper MA et-al. Phaeochromocytoma in pregnancy. Five cases and a review of the literature. British Journal of Obstetrics and Gynaecology. 1989.



SOAP 2017