///2009 Abstract Details
2009 Abstract Details2018-05-01T17:45:11+00:00

Comparing the effects of 5 μg Sufentanil and 25 μg Fentanyl on intrathecal Bupivacaine for caesarian delivery in Pregnancy Induced Hypertension.

Abstract Number: 51
Abstract Type: Original Research

RAVINDER DATT BHANOT DNB ( Diplomate in National Board) Resident1 ; DR THRISSUR R RAMACHANDRAN MD2; DR RAJI SHARMA MD3; DR DAVID GEORGE VELIATH MD4; DR RANJAN R V DA, DNB5

Background : The study was designed to evaluate & compare the effects of sufentanil or fentanyl on intrathecal bupivacaine for caesarian delivery in pregnancy induced hypertension.

Patients & methods: Sixty parturients of ASA physical status II scheduled for elective lower uterine caesarian section were divided into three groups. Group A served as control and received only. 5% hyperbaric bupivacaine 7.5mg, Group B received 25μg fentanyl citrate

with hyperbaric bupivacaine and Group C received 5g sufentanil citrate with hyperbaric bupivacaine. Severity of pain was assessed by

visual analogue scale (VAS).The patients were followed up and outcome analyzed.

Results: The patients of group C experienced superior quality of intra-operative analgesia during periods of intense stimulation like delivery of the baby and peritoneal toileting before wound closure. Patients belonging to group B and group C were absolutely pain free for the first hour following surgery. But patients in control group experienced mild pain (VAS - 15.00 7.78) at 60 minutes postoperatively. Total duration of analgesia was highest in group C (233.75 13.07 minutes) than group B (226.20 6.66 min.) and control group (136.85 10.61 minutes). Incidence of nausea and vomiting was significantly less in group B (20%) and group C (10%) as compared to control group (50%). Few patients in group C experienced mild pruritus. All the patients remained Haemodynamically stable during the

entire study period. There was no incidence of respiratory depression with intrathecal fentanyl and sufentanil. There was no adverse neonatal outcome.

Conclusion: Sufentanil or fentanyl improved the quality of subarachnoid block with heavy bupivacaine in pregnancy induced hypertensive patients for caesarean section. The duration of action was longer with sufentanil than fentanyl. All patients were haemodynamically stable during Intra and postoperative period. There were no adverse effects in the mother and the newborn.

SOAP 2009