///2009 Abstract Details
2009 Abstract Details2018-05-01T17:45:11+00:00

Habitual snoring in pregnancy and fetal umbilical arterial blood gases

Abstract Number: 22
Abstract Type: Original Research

Alexandra S. Bullough MBChB FRCA1 ; Louise M O'Brien PhD2

Introduction: Sleep disordered breathing (SDB) describes a spectrum of sleep-related breathing abnormalities which range from snoring to obstructive sleep apnea. Habitual snoring (i.e., snoring ≥3 nights/week) is commonly used to identify those at risk of obstructive sleep apnea. Emerging data suggests that habitual snoring in parturients may be a risk factor for adverse fetal outcome such as growth retardation. Change in fetal heart rate, as well as intrauterine growth retardation, has been reported in case studies although research investigations are few and the available literature is conflicting. Umbilical arterial blood pH and gas analysis have been recognized as a reliable indication of fetal oxygenation and acid-base condition at birth, yet no studies of maternal SDB have included these fetal outcomes. Given the potential impact of habitual snoring on fetal outcome, data are urgently required to address this significant public health issue.

Methods: As part of a larger study investigating the impact of SDB on maternal and fetal outcomes, women ≥18 years old were recruited during their last trimester of pregnancy and invited to complete several sleep questionnaires. Consent was obtained to access medical records for delivery information. Women in the present study included only those who had an uncomplicated, full term, normal vaginal delivery of a singleton fetus. SDB was defined as the presence of habitual snoring and women were classified as SDB or controls. Umbilical arterial blood gases included arterial pH, pCO2, HCO3 and Base Excess (BE) and were compared between the two groups of parturients.

Results: There were 229 pregnancies included in the analysis with a mean age of 29.92. In total, 28% of women reported SDB. No significant differences were found for any umbilical arterial gases between the SDB and control group: pH, 7.270.09 vs. 7.260.6; pCO2 54.411mmHg vs. 57.410mmHg; HCO3 23.62.32mmol/L vs.24.362.47mmol/L; and BE -1.823.25mmol vs. -1.852.20mmol respectively.

Conclusions: In otherwise normal pregnancies, our preliminary findings do not support an association between maternal SDB and adverse fetal outcome, as measured by umbilical arterial blood gases.

SOAP 2009